BioAnalyst™ Software

BioAnalystTM Software is a comprehensive, fully integrated set of data processing tools within Analyst® Software for the identification and characterization (e.g. post-translational modifications) of peptides and proteins using mass spectrometry data.

- Reconstruction tools for manual and automated molecular weight determination from LC/MS, MS and MS/MS data
- Peptide mapping tools for automated matching of LC/MS data to predicted peptides in a known protein sequence including a Protein Editor for performing virtual digestions with modifications and direct links back to raw MS data
- Proprietary de novo sequencing algorithm for automated sequencing of peptides from unknown proteins including a Peptide Editor for computing fragment ion masses of peptides which can be directly linked to raw MS/MS data for labeling and data presentation
- PepSeaTM Server from Protana provides single spectrum database search capabilities using peptide molecular weights, peptide fragments, sequence tags, amino acid sequence, protein name and accession number
- Data Dictionary, the single source for all chemical information, provides a dynamically linked molecule editor to easily define modifications, custom amino acids, adducts, nucleic acids, and cleavage agents
- Supports QTRAP® Systems, Triple Quad Systems, and the TripleTOFTM 5600 System

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LipidView™ Software

LipidView™ Software is a data processing tool for the molecular characterization and quantification of lipid species from electrospray MS data. The software enables lipid profiling by searching parent and fragment ion masses against a lipid fragment database containing over 25,000 entries, and reports a numerical and graphical output for various lipid molecular species, lipid classes, fatty acids and long chain bases*. LipidView™ software streamlines a number of key steps such as automated data processing derived from template methods, method editing and selection, lipid species identification, comprehensive isotope contribution removal, multiple internal standards-based quantification, visualization and result reporting. Combined with the AB SCIEX QTRAP® 5500 System, or the AB SCIEX TripleTOF™ 5600 System, this complete hardware and software package offers unique data acquisition strategies coupled with automated data processing for lipid profiling.

AB Sciex s.r.o. Chemický priemysel

LightSight® Software

LightSight® Software is the ultimate tool for finding metabolites. In a few simple steps, highly optimized acquisition methods can be created to detect metabolites with unprecedented effectiveness. This allows for open access metabolite identification experiments on a QTRAP® system with minimal operator training. The streamlined acquisition process gives ADME Scientists rapid and highly relevant results. LightSight® software makes the work of identifying metabolites more efficient than ever, with a workspace that supports quick, effective decision-making. LightSight® software s exceptionally clear data display eliminates the need for tedious visual comparison of printouts. Non-mass spectrometric analog data (e.g. UV- or radioactive-detector chromatograms) can be simultaneously analyzed in LightSight® software v2.2.1, giving one the ability to correlate MS-based structural information with quantitative analog data.

AB Sciex s.r.o. Chemický priemysel

DiscoveryQuant™ Software

DiscoveryQuantTM Software - compatible with our Triple Quadrupole and QTRAP® hybrid systems - improves the speed of analysis and information gathering of drug candidates in high-throughput early ADME (absorption, distribution, metabolism, and excretion) studies. With a simple and elegant workflow, DiscoveryQuantTM Software is a comprehensive software solution that streamlines the drug discovery process by providing better efficiency and productivity. To download a trial version and obtain license keys, visit our DiscoveryQuant™ Trial Software Download Registration Site - Automated, high quality optimization: High success rate through innovative Saturation Control and MRM-based optimization. - Increase the Speed of Discovery: Manages the entire workflow - from optimizing compounds to report generation. - Smooth integration into your laboratory: All major LC systems fully supported, so you can choose the best equipment.

AB Sciex s.r.o. Chemický priemysel

Cliquid® Software

Cliquid® 3.2 Software for Routine Screening and Quantitation is designed to work in conjunction with Analyst® Software Version 1.5.2 (or higher) to provide a simple four step workflow by LC/MS/MS. The software can be used with any AB SCIEX QTRAP® or triple quadrupole LC/MS/MS system. While Cliquid® 3.2 Software itself does not include any pre-configured tests, a number of pre-configured iMethod™ Applications, including libraries and MRM catalogues, are available for Food, Environmental, Forensic and Clinical Research analysis. Visit our iMethod Application Center for a complete list of available iMethods. To download a trial version and obtain license keys, visit our Cliquid® Trial Software Download Registration Site - Bi-directional LIMS compatibility with any LIMS or LIS (not standard with Cliquid® Software 3.2) - Barcode reading for chain of custody workflows - Secure user log-in functionality links the identity of operators to the tasks they are allowed to perform - Customizable, simple four-step workflow makes set-up and run analysis easy - New, improved and faster reporting tool provides you the ability to choose from hundreds of available Microsoft Word, Excel, .PDF or text based report styles or customize these according to laboratory specific requirements - Simplified data analysis, re-integration and re-processing tool - Support for routine quantitation, targeted, and unknown screening workflows - Support for walk up Open Access compound identification and verification - Full compatibility with Analyst® Software version 1.5.2 (or higher) and ChemoViewTM Software version 2.0.2 - Available iMethod™ Applications, MRM catalogues (with up to 6 transitions per compound) and MS/MS Libraries - Pack/Unpack method sharing functionality - Multi-lingual interface and reporting - Full control of all industry leading HPLC systems - Support for multiplexing HPLC systems into a single mass spectrometer

AB Sciex s.r.o. Chemický priemysel

ChemoView™ Software v2.0.2

ChemoViewTM Software 2.0.2 is designed for data processing to quickly screen a series of compounds in a large set of flow injection triple quadrupole mass spectrometry (FI/MS/MS) data generated in Analyst® Software. The concentrations and equations of concentrations for all compounds are determined. If the acceptance limits for the compounds have been established, the program highlights the samples having results outside of the limits. To download a trial version and obtain license keys, visit our ChemoView™ Trial Software Download Registration Site - Easily relate the method process and method test details with tests results and the associated audit trail history. - Automatically batch process results across different sample types to increase the speed and efficiency of reporting - Archive results and search by report name, date, wiff file or sample name. - Specify the composition type per sample i.e. blood, bile, etc, and associate this with report limits and user defined calculations for the generation of results. - Specify test limits for each analyte within an analysis as well as view and automatically flag the results generated if they fall outside of user defined limits. - Designate a specific report template by processing method from a wide range of standard reports that can also be easily customized according to specific test requirements.

AB Sciex s.r.o. Chemický priemysel

Analyst® Software

As the World s most commonly used LC/MS/MS instrument control software platform with more than 10,000 users worldwide, Analyst® software provides state of the art functionality for instrument control, data analysis, reporting and audit trail. The latest version of Analyst Software builds on this legacy by providing new features that both enhance performance as well as ease of use. - Security and audit trail features to enable 21 CFR part 11 compliance - The Scheduled MRM™ Algorithm that provides the ability to use overlapping MRM monitoring periods to maximize quantitative performance and accuracy - now with the ability to use polarity switching - The Dynamic Background Subtraction™ Algorithm that provides the ability to subtract the baseline background ions dynamically during a run in order to detect underlying peaks - Industry leading integration algorithms for the most accurate quantitation results - An Integration Quality measure for each peak to reduce the need for manual data review - Faster Peak Review and Reporting with the included Reporter 3.2 Software - Support for Windows 7, 32-bit

AB Sciex s.r.o. Chemický priemysel

Standards & Reagents

- aTRAQ™ Kits for Amino Acid Analysis in Hydrolysates - aTRAQ™ Kits for Amino Acid Analysis in Hydrolysates - aTRAQ™ Kits for Amino Acid Analysis in Physiological Fluids - aTRAQ™ Kits for Amino Acid Analysis in Physiological Fluids - Chemical Standards Kits - The Chemical Standards Kits contain reagents for calibration, tuning, and optimization of AB SCIEX QTRAP®, Triple Quad™, TripleTOF™, TOF/TOF™, and MALDI-TOF Systems. - Cleavable ICAT® Reagents - Amino Acid 20/20 Analyzer, the first complete mass spectrometry system for amino acid analysis, enables you to quantitate 20 amino acids from protein hydrolysate samples twice as fast as existing chromatography systems. - CYP450 Protein Assay - Human Induction Kit - The CYP450 Protein Assay - Human Induction Kit, uses an LC/mass spectrometry workflow to enable direct measurement of protein expression changes of individual CYP450 isoforms with high specificity, sensitivity, and accuracy. - iDQuant™ Standards Kit for Pesticide Analysis - The iDQuant™ Standards Kit for Pesticide Analysis contains 206 common pesticides and can be used for quantifying and identifying pesticides in any sample matrix. - iTRAQ® Reagents - The iTRAQ® Reagents are the first set of multiplexed, amine-specific, stable isotope reagents that can label all peptides in up to eight different biological samples enabling simultaneous identification and quantitation, both relative and absolute, while retaining important PTM information. - mTRAQ® Reagents - The mTRAQ® Reagents are amine-specific, stable isotope labeled reagents, available in duplex or triplex format, designed for high confidence protein and peptide biomarker verification using MRM analysis on QTRAP® systems and the Triple Quadrupole Mass Spectrometers.

AB Sciex s.r.o. Chemický priemysel

iMethod™ Tests for Food & Beverage

iMethod™ Test for Pesticide Screening Version 2.0 for Cliquid® Software General food products AB SCIEX Carbamate, Phenyl Urea, Triazine, Organophosphorus and Acidic Pesticides. This iMethod also includes a screening method using the MRM ? EPI workflow to collect full scan positive ionization MS/MS spectra and an MRM catalogue of over 600 pesticides, with up to 6 transitions per compound. Phenomenex SYNERGI 4 µm Fusion-RP 80? 50 x 2 mm column and a Phenomenex Synergi 2.5 ?m Fusion 100 ?, 50 x 2 mm HPLC column are included. Part no: 1037144 iMethod™ Test for Nitrofuran Metabolites Version 1.0 for Cliquid® Software General food products such as seafood, meat, eggs, etc. AB SCIEX Nitrofurans and metabolites in food products. Phenomenex LUNA 3 µm C18(2) 150 x 2 mm column is included. Part no: 1034365 iMethod™ Test for Melamine and Cyanuric Acid for Cliquid® Software (Partner Contributed) Milk and dairy products Phenomenex Melamine and Cyanuric Acid in milk and dairy products for 3200 QTRAP® LC/MS/MS System and Shimadzu Prominence iMethod™ Test for Malachite Green Version 1.0 for Cliquid® Software Seafood AB SCIEX Malachite green in seafood. Phenomenex SYNERGI 4 µm Max-RP 80? 50 x 2 mm column is included. Part no: 1034369 iMethod™ Test for Fluoroquinolones Version 1.0 for Cliquid® Software Meat AB SCIEX Quinolone and fluoroquinolones antibiotics in meat products. Download this for free. iMethod™ Test for Azo Dyes Version 1.0 for Cliquid® Software Spices AB SCIEX 13 azo-dyes including 6 Sudan Dyes, Dimethyl Yellow and Para Red in spices and sauces. Phenomenex LUNA 5 µm C8 150 x 2 mm column is included. Part no: 1034366 iMethod™ Test for Tetracycline Antibiotics for Cliquid® Software (Partner Contributed) Meat Spark Holland 5 Tetracyclines in meat samples iMethod™ Test for Sulphonamide Antibiotics using Online SPE for Cliquid® Software (Partner Contributed) Meat Spark Holland 8 Sulphonamides in meat samples using a Spark Holland online SPE system, 3200 QTRAP® LC/MS/MS System & Shimadzu Prominence iMethod™ Test for Penicillin Antibiotics using Online SPE for Cliquid® Software (Partner Contributed) Meat Spark Holland 8 Penicillins in meat samples iMethod™ Veterinary Antibiotic LC/MS/MS Library Version 1.1 for Cliquid® Software Meat & food products AB SCIEX Antibiotics, including 139 veterinary antibiotics and their metabolites. This library contains an MRM catalogue and spectral library. Part no: 5008156 iMethod™ Test for Antibiotic Screening Version 1.1 for Cliquid® Software Meat, dairy, fish and other animal products AB SCIEX Antibiotics, including: beta-lactam, tetracycline, sulfonamide, macrolide, amphenicol, fluoroquinolone and flunixin. Phenomenex 3.0 ?m 110?, Gemini C18, 50 x 2 mm HPLC column is included. Part no: 5008145 iMethod™ Test for Aflatoxins for Cliquid® Software (Partner Contributed) General food products Phenomenex Aflatoxins B1, B2, G1 and G2 in food samples. This uses Aflatoxin M1 as an internal standard iMethod™ Test for Acrylamide Version 1.0 for Cliquid® Software Starch-enriched food AB SCIEX Detect acrylamide in cooked starch-enriched food. Phenomenex LUNA 3 µm C18(2) 150 x 3 mm column is included. Part no: 1034371 iMethod™ Test for Melamine and Cyanuric Acid Version 1.0 for Cliquid® Software Pet food AB SCIEX Melamine and Cyanuric Acid in pet foods with 3200 QTRAP® LC/MS/MS System and Agilent 1100 iMethod™ Test for Carbamates for Cliquid® Software Beverages Phenomenex Seven Carbamates and their internal standards in beverage samples. iMethod™ Pesticide LC/MS/MS Library Version 1.0 for Cliquid® Software Library General food products AB SCIEX This contains an MRM catalogue and spectral library which both provide information on the most common 636 pesticides and their metabolites that are required to be monitored in vegetables or other food products. Part no: 1037032 iMethod™ Test for Tetracycline Antibiotics using Online SPE for Cliquid® Software (Partner Contributed) Meat Spark Holland This test is for the analysis of five Tetracyclines in meat samples using a Spark Holland online SPE system. Use this for the 3200 QTrap and Shimadzu Prominence. iMethod™ Test for Chloramphenicol in Shrimp Version 1.1 for Cliquid® Software General food products AB SCIEX CAP residues in food products in a low concentration range. Phenomenex AQUA 5 µm C18, 125?, 50 X 2 mm column is included. Part no: 1034370 iMethod™ Test for Triazine Pesticides in Water Version 1.0 for Cliquid® Software Food AB SCIEX Detect pesticides in food. LC Column: Phenomenex Kinetex, C18, 50 x 2.1 mm, 2.7 ?m, Cat No 00B-4462-AN

AB Sciex s.r.o. Chemický priemysel

iMethod™ Tests for Forensics

iMethod™ Test for Drugs of Abuse Screening Version 2.0 for Cliquid® Software Blood, urine, hair & saliva AB SCIEX 1250 drugs of abuse and related compounds, with up to 6 transitions per compound. The MRM catalogue can be used to create additional custom screening and / or quantification methods. The positive ion iMethod Test now contains 700 compounds. The previous 300 compound iMethod™ Test is also included. Includes Restek AB Forensic LC Column, Guard and Hardware. Part no: 1040049 iMethod™ Test for THC-COOH using the Spark Pico System Version 1.0 for Cliquid® Software (Partner Contributed) Urine Spark Holland THC-COOH in urine using Spark™ Pico system for automated, on-line solid phase extraction followed by analysis on an API 4000™ System. Phenomenex Gemini C6-Phenyl, 3 µ, 3 x 50 mm analytical column (P/N 00B-4257-B0) should be purchased directly from Phenomenex. iMethod™ Test for NIDA 5 Drugs Version 1.0 for Cliquid® Software Urine AB SCIEX NIDA 5 Drugs using the API 3200™ or the API 4000™ Systems. Restek® Analytical Column, 5µm, DB Biphenyl Column, 50 x 2.1 mm (P/N 9409552) is included. Part no: 1034375 iMethod™ Test for Nicotine and Metabolites V1.0 Urine AB SCIEX Nicotine and Metabolites using the API 3200™ or the API 4000™ Systems. Phenomenex Synergy Max-RP 4.0 µm 80A, 100 x 2 mm is included Part no: 104680 iMethod™ Forensic LC/MS/MS Library Version 1.0 for Cliquid® Software Blood, urine, hair & saliva AB SCIEX 1250 compounds. Can be used stand-alone to create custom screening and/or quantification methods or in conjunction with the iMethod™ Test for Drugs of Abuse Screening (not included but available for purchase) to provide confirmation. Part no: 1034271 iMethod™ Test for Benzodiazepines Version 1.1 for Cliquid Software Blood, urine & plasma AB SCIEX 30 Benzodiazepines in Plasma, Blood or Urine. Includes a Phenomenex 80 ?, Synergi 4 µm Hydro - RP, 50 x 2 mm (P/N 00B-4375-B0). Part no: 1034374 iMethod™ Test for Pain Panel Version 1.0 for Cliquid® Software Urine AB SCIEX This iMethod™ Test contains a method for the routine analysis of either 15 (short panel) or 41 (long panel) drugs associated with pain panel in urine samples.

AB Sciex s.r.o. Chemický priemysel

iMethod™ Tests for Environmental

iMethod™ Test for Herbicides in Water (Partner Contributed) Water Spark Holland 22 herbicides in water by on-line SPE and LC/MS/MS according to DIN 38407-35 using the Spark Holland Pico System with on-line sample clean up iMethod™ Test for the analysis of Glufosinate, Glyphosate, and its metabolite AMPA in Water (Partner Contributed) Water Spark Holland Glufosinate, Glyphosate and AMPA in water using the Spark Holland Pico System with on-line sample clean up iMethod™ Test for Bisphenol, Octylphenol and Nonylphenol for Cliquid® Software (Partner Contributed) Water Spark Holland Bisphenol, Octylphenol and Nonylphenol in water samples. Use with the 4000 QTRAP® LC/MS/MS System and the Dionex Ultimate 3000. iMethod™ Test for Ethanolamines Version 1.0 for Cliquid® Software Water AB SCIEX To monitor the removal of ethanolamines from industrial discharged waste water and the extent of human and environmental exposure to nitrogen mustards, a quantitative analytical method is desired. iMethod™ Test for Ethanolamines Version 1.0 for Cliquid® Software Water AB SCIEX To monitor the removal of ethanolamines from industrial discharged waste water and the extent of human and environmental exposure to nitrogen mustards, a quantitative analytical method is desired. iMethod™ Test for Bisphenol, Octylphenol and Nonylphenol for Cliquid® Software (Partner Contributed) Water Spark Holland Bisphenol, Octylphenol and Nonylphenol in water samples. Use with the 4000 QTRAP® LC/MS/MS System and the Dionex Ultimate 3000. iMethod™ Test for Herbicides in Water (Partner Contributed) Water Spark Holland 22 herbicides in water by on-line SPE and LC/MS/MS according to DIN 38407-35 using the Spark Holland Pico System with on-line sample clean up iMethod™ Test for the analysis of Glufosinate, Glyphosate, and its metabolite AMPA in Water (Partner Contributed) Water Spark Holland Glufosinate, Glyphosate and AMPA in water using the Spark Holland Pico System with on-line sample clean up

AB Sciex s.r.o. Chemický priemysel